Combinatorial library Designing

User 4b8a3205dc

14-05-2007 11:30:39

Hi,





I am trying to design a combinatorial library for a molcule. i have the scaffold. So using the synthesizer program can i generate a combinatorial library?





if so.. can u please tell me how could i select the R groups and reactions for the same.





regrads,


Jiji

User 4b8a3205dc

15-05-2007 08:24:33

one more doubt,


in synthsiser also for synthesisng molecule, reactor is used.So what the main difference between reactor and synthesis??

ChemAxon e08c317633

15-05-2007 11:25:24

jijibio wrote:
one more doubt,


in synthsiser also for synthesisng molecule, reactor is used.So what the main difference between reactor and synthesis??
Main differences:





1. Reactor processes one reaction step at a time, while Synthesizer processes a sequence of reactions taking their reactants from and putting their products into predefined molecule sets.


2. Synthesizer works also in database mode. Reactor works on databases only trough JChem Cartridge.





Note: Synthesizer is currently under redesign. We will make it easier to use.





Synthesizer manual: http://www.chemaxon.com/jchem/doc/user/Synthesizer.html


Useful examples: http://www.chemaxon.com/jchem/examples/synthesizer/index.html





We will answer the rest of your questions soon.





Best regards,


Zsolt

ChemAxon e08c317633

22-05-2007 14:41:41

I forgot to mention an additional difference: Reactor has graphical user interface (GUI), so it is easier to use.





Please try Reactor, and let us know if it doesn't suits your needs.





Zsolt