synthesiser scaffold

hi,





suppose i fragmented one drug molecule using the 'Fragmenter' and got the result file of 14 molecules.now i want to resynthesise that fragmnets using 'Synthesiser program'. so how can i select the scaffold and R gropus from my fragment??/





if i'm using 'Reactor' instead if 'Synthesiser' how can i select the appropriate reaction from the library or how can i define the raection scheme??/

The Reactor tool (and Synthesizer) works with compounds and not with fragments, furthermore, no R-groups are needed for virtual synthesis. So they are probably not relevant here.





I am not sure, what you mean on "resynthesizing a fragment". There are lots of information available on our web site, but you need to select the right tool for your purpose. Please explain your task, and I try to help. Example pictures would be very useful.