What is "Strongness" parameter in Acidic pKa calcu

User 1126886aa7

27-08-2010 11:17:47

 Hi,


 


I am currrently using JChem for Excel ,can nyone pls tell wat is "Strongness" parameter in Acidic pKa calculation?


looking forward to your reply,

ChemAxon e08c317633

31-08-2010 19:19:06

Multiprotic molecules have more than one ionizable atom, and so they can have more than one acid dissociation constant. See the attached image. With "Strongness = 1" setting the strongest acidic pKa is calculated, with  "Strongness = 2" setting the second strongest acidic pKa, and so on.


Zsolt