Has anyone tried to calculate the Abraham descriptors using chemaxon (J Pharm Sci. Vol. 90: 749 - 784)?
The abraham descriptors are:
E - excess molar refraction
S - dipolarity/polarizability
A - hydrogen bonding acceptors
B - hydrogen bonding donors
V - McGowan characteristic volume
These descriptors are included in the ABSOLV module which is now part of ACDlabs