I have 2 tautomers structures (see attached file).
Why I have not the same calculated LogP value with cxcalc?
LogP= 3,302 : tautomer1.mol
LogP=3,767 : tautomer2.mol
The tautomerization option can be invoked in the cxcalc.
"cxcalc logP -M true "your molecule"
The "M" option means that the major tauotmeric form of "your molecule" will be the subject of the logP calculation.
I don't know whether you tried this "M" option or not.
I have tried the "M" option. My conclusion is that the two logP values
will be different either the "M" option is adjusted or not.
The reason is that the predicted major tautomeric form of "10H-anthracen-9-one" will remain itself.
And the predicted major tauotmeric form of "anthracen-9-ol" will remain itself as well.
So it means that "10H-anthracene-9-one" and "anthrace-9-ol" are stable
tautomeric structures according to our prediction. This is why their
logP will be different.