LogP Plugin Problem

User a9d76a1173

06-06-2014 21:02:45

Following code runs OK as a unit test. However, the method doesn't work when ran through a javafx task thread. It seem to block the task thread. With a finally block, it always return 100.0.


 


public static Double calcLogP(String smiles) {


        Double clogP = 100.0;


        try {


            logPPlugin plugin = new logPPlugin();


            // set logP calculation method


            plugin.setlogPMethod(logPPlugin.METHOD_WEIGHTED);


            // set method weights


            plugin.setWeightOfMethods(1, 2, 1, 0);


            // set parameters


            plugin.setCloridIonConcentration(0.2);


            plugin.setNaKIonConcentration(0.2);


            // set result types


            plugin.setUserTypes("logPTrue");


            Molecule m = MolImporter.importMol(smiles);


            m.dearomatize();


            Hydrogenize.addHAtoms(m);


            // set the input molecule


            plugin.setMolecule(m);


            // run the calculation


            plugin.run();


            // get the overal logP value


            clogP = plugin.getlogPTrue();


            if (clogP.isInfinite() || clogP.isNaN())


            {


            clogP = 100.0;


            }


        } catch (Exception e) {


            LOGGER.error("An error occured while calculating LogP",e);


        }


        return clogP;


    } 

ChemAxon 5fc3e8d7d0

25-06-2014 10:13:34

Dear Lochana,

We are sorry for the very late answer.

We can not reproduce your issue. We attached an example code, it works fine.
Could you send us a working example which produce the mentioned problem?

Best regards,
Laszlo