User 81a38f9467
03-01-2013 01:15:57
I am using MarvinSketch 5.11.4. When the Stereoisomers Plug-in is used to generate tetrahedral stereoisomers of the attached structure, four isomers are generated { (R,R), (S,S), (R,S) and (S,R) }. Only the first two structures are reasonable, so I expected that the "Filter invalid 3D structures" option would remove the (R,S) and (S,R) isomers. But what actually happens is that three of the four isomers are filtered out, leaving just the (S,S) isomer. Why is the other enantiomer removed ? The correct output should be both the (R,R) and the (S,S) stereoisomers.