Structure Checker: Chiral Flag checking w/ symmetric compds

User 81a38f9467

10-12-2010 21:28:48

I'm using Structure Checker 5.4.0.0.  I ran three structures which incorrectly had chiral flags through the Chiral Flag Error Checker;  only one of the three was successfully identified as having an inappropriate chiral flag.  Many symmetric compounds with stereogenic centers are incorrectly assigned chiral flags.  I would like the Chiral Flag Error Checker to correctly be able to strip inappropriate chiral flags from structures such as these examples.

ChemAxon d76e6e95eb

15-12-2010 19:23:14

Thank you for this report, we will improve our chirality detection to handle these compounds properly in 5.4.1 release.