Tautomerize gives aromatic output. Dearomatize fails.

User 81a38f9467

02-12-2010 20:56:40

I'm using Standardizer 5.4.0.0.  When I input the attached molecule and use the Tautomerize action, the output is an aromatic form.  It is my understanding that Tautomerize should produce dearomatized outputs.  Furthermore, if I run the same compound through using Tautomerize then Dearomatize, the output is still in the aromatic form. 


Please let me know how I can get the dearomatized output for this compound.

User 851ac690a0

02-12-2010 22:02:07

Hi,


 


I have tried  the " tauotmerize tool" of Marvin  on the on official site (with the version 5.4.0).  I got 3 dearomatized structures. See the attached picture. 


 Is there a bug  in the standardizer code(?). One of my collegaue will respond soon.     


Jozsi

User 851ac690a0

03-12-2010 01:20:45

Hi,


 


I was able to repeat your bug.  This bug  is really in the dearomatization step. I fixed it. 


The fixed version will appear asap.


 


Jozsi