Problem with CL Standardizer

User bc9a7e94b9

26-04-2009 21:55:54

Hi,


When trying to standardize a set of SMILES strings from the command line, I'm getting the following type of error:


WARNING: Chiral center has wrong connectivity at atom 2 in smiles: O[C@H](C\C(=C/C=C/1\CCC[C@@](C)([C@@H](CC[C@H]([C@H](C)CCCC(O)(C)C)2)\1)2)\C(=C)[C@@H](O)C1)1
The chirality is ignored.


 


The command I ran from the command prompt is as follows:


standardize 2008LiData.smi -c flo-standard.xml -o 2008LiData_CL.smi >> 2008LiData_CLStand2.txt 2>&1


 


I am using JChem version 5.1.3,  Windows XP professional OS. I attach all relevant files.


 


I did not receive any errors when I copied this SMILES in to the Daylight depiction utility.


The only references I've found to this type of problem in this forum suggest that this was a bug in older versions of JChem.


Am I doing something wrong?


 


Many thanks for any assistance.


 


Richard Marchese

ChemAxon 25dcd765a3

27-04-2009 16:53:42

Hi,


It seems to be a bug. We fix it asap.


 


Andras

ChemAxon 25dcd765a3

27-04-2009 18:11:11

Hi,


 


I have fixed the bug.


Thank you for the report.


The next version will contain the fix.


 


Andras

User bc9a7e94b9

27-04-2009 19:20:08

Thank you.


 


Are you in a position to say when the next release will be?

ChemAxon 990acf0dec

28-04-2009 15:49:08

Hi,


The 5.2.2 version is planned to be released by the end of May.


Best regards,


Akos