ChemAxon b124dd5f17
29-03-2005 09:42:29
Title: LeadMarker(TM) - an integrated suite for managing chemical and biological infomation
Authors: Tim Dudgeon*, Robert Bamford#, Chris Palmer&
Institutions: * Informatics Matters Ltd., Oxford, UK. # Managed Ventures llc, Irvine, CA, USA. & KCC Tech Pty Ltd, 2 Alpha Avenue, Currumbin 4223, Queensland, Australia
Abstract: We present LeadMarker(TM), a suite of tools which provide a customizable solution for acquiring and managing information generated as part of the drug discovery process. LeadMarker(TM) contains a chemical registration system (chemMarker) capable of managing small and large sets of chemical libraries; A sample management system (sampleMarker) capable of registering chemical information from single vials to high density source plates and tracking reformatting applications during the screening process; A unique module for acquiring screening data from a variety of detection instrumentation (assayMarker); processing the data to identify active chemicals and managing the screening campaign for any given biological target; and finally a high performance Java based chemical spreadsheet tool that can be used for processing and analyzing chemical and biological data (structShare).
Authors: Tim Dudgeon*, Robert Bamford#, Chris Palmer&
Institutions: * Informatics Matters Ltd., Oxford, UK. # Managed Ventures llc, Irvine, CA, USA. & KCC Tech Pty Ltd, 2 Alpha Avenue, Currumbin 4223, Queensland, Australia
Abstract: We present LeadMarker(TM), a suite of tools which provide a customizable solution for acquiring and managing information generated as part of the drug discovery process. LeadMarker(TM) contains a chemical registration system (chemMarker) capable of managing small and large sets of chemical libraries; A sample management system (sampleMarker) capable of registering chemical information from single vials to high density source plates and tracking reformatting applications during the screening process; A unique module for acquiring screening data from a variety of detection instrumentation (assayMarker); processing the data to identify active chemicals and managing the screening campaign for any given biological target; and finally a high performance Java based chemical spreadsheet tool that can be used for processing and analyzing chemical and biological data (structShare).